Everolimus-D4 solution, 100 mug/mL in acetonitrile, ampule of 1 mL, certified reference material

Code: E-070-1ML D2-231

General description

A stable-labeled internal standard for the immunosuppressant Everolimus, marketed as Zortress® and Certican for use in organ transplantati...


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€588.10 1ML
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General description

A stable-labeled internal standard for the immunosuppressant Everolimus, marketed as Zortress® and Certican for use in organ transplantation and Afinitor® for treatment of kidney and pancreatic cancers. Clinical laboratories quantitate everolimus levels in patient whole blood samples using LC-MS/MS. While many everolimus LC-MS/MS methods use 32-desmethoxyrapamycin or ascomycin as an internal standard, higher levels of variability / lower levels of reproducibility may occur in the analysis along with the potential for interferences. Use of a stable-labeled analog of everolimus is the best choice to minimize variability or mitigate any potential interference in LC-MS/MS analysis.

Legal Information

Snap-N-Spike is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

CERILLIANT is a registered trademark of Cerilliant Corporation

Zortress is a registered trademark of Novartis AG

Afinitor is a registered trademark of Novartis AG

application(s)clinical testing
concentration100 µg/mL in acetonitrile
featureSnap-N-Spike®/Snap-N-Shoot®
formliquid
formatsingle component solution
gradecertified reference material
InChI keyHKVAMNSJSFKALM-ULVVDLMCSA-N
InChI1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/i24D2,25D2
manufacturer/tradenameCerilliant®
packagingampule of 1 mL
Quality Level300
SMILES string[2H]C([2H])(O)C([2H])([2H])OC1CCC(CC(C)C2CC(=O)C(C)C=C(C)C(O)C(OC)C(=O)C(C)CC(C)C=CC=CC=C(C)C(CC3CCC(C)C(O)(O3)C(=O)C(=O)N4CCCCC4C(=O)O2)OC)CC1OC
storage temp.−70°C
technique(s)gas chromatography (GC): suitable, liquid chromatography (LC): suitable
Cas Number1338452-54-2
Hazard Class3
Un Number1648
Pack GroupII
This product has met the following criteria to qualify for the following awards:



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